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I've got a new Acer PC here at work that they want me to uninstall all of the bloat-ware that Acer put on there.
Every freakin' one of them is throwing up that message, and they have never even been run before.
What a PITA, rebooting after uninstalling every one. Just for future reference, I had this problem and solved it by killing processes Trusted Installer and a particular whose command-line (seen in Process Explorer) mentioned something about uninstalling. By doing so, windows will tell you which programs are still in use.
After it restarts, try to uninstall the same program you did before, it should most likely work again.
If you are not the only person on the computer, its impossible to know what the other users have done while you were not there, If there are no programs running actively, it sounds like some kind of weird glitch I've never heard of.
In my particular case it appears that a background process (tivoli endpoint manager or possibly a virus scanner auto updating itself or what not) was installing a program I was "unaware" of in the background. Or possibly disable the system service that is firing off the background installs.
So common advice on the interwebs seems to be to kill "msiexec.exe" or "trustedinstaller.exe" or "installmanager.exe" if any of those exist in the process list. Or reboot if those all fail (though if its a service doing the installs, the problem will just come back again, you may have to just wait it out until it finishes first).
If all of those fail then possibly using the Revo Uninstaller will still work, but you always hope to not need to install 3rd party software to uninstall others :| Or of course, you could just wait Thank you for your interest in this question.
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KB18 This article explains the difference between the ACML int64 and 64bit versions.