She has also appeared alongside Saturday Night Live cast member Fred Armisen in the music video for the song "Rabbit Habits" by Philadelphia experimental band Man Man. The duo share one electric guitar and both sing lead vocals.
In 2006, they released their debut album, The Farewell Album, produced by John Spiker, bassist of Tenacious D.
Yi was featured in the video "Song Away" by Hockey.
In January 2010, Yi performed a duet about break-up lines (the opposite of pick-up lines) with Demetri Martin on the episode "2" for the Comedy Central sketch series Important Things with Demetri Martin.
However, the duet was cut from the final edit of the episode.
From October 2011 to May 2012, Yi starred in Fox's series House as Dr.
Someone sent me an article that said I was really sad.
After Star magazine reported Canadian funnyman Michael Cera had dumped his “girlfriend,” comedian Charlyne Yi after dating for three years, Yi set the record straight to Moviefone. or ever,” Yi said of the time her and Cera spent together shooting the mockumentary “Paper Heart.” “I also heard that we broke up.
Someone sent me an article that said I was really sad. But he’s actually in Toronto right now filming a movie called ‘Scott Pilgrim.’ So that’s interesting.” Yi, best known for her role as a stoner in the Judd Apatow movie “Knocked Up,” makes her feature film writing debut with “Paper Heart.” The movie follows Yi (who claims not to believe in love) on her quest to understand the very thing she doesn’t understand.
Stay tuned for and POP’s review of “Paper Heart” this Friday!
In one performance, she had her head shaved while she sang the song "Nothing Compares 2 U".
Her screenwriting debut, the feature film Paper Heart, won the Waldo Salt Screenwriting Award at the 2009 Sundance Film Festival. Chi Park in the medical drama House, alongside Hugh Laurie as one of the doctors on House's team.
She attended the University of California, Riverside before leaving to pursue a full-time career in comedy.
She had an early interest in performing when she attended Bloomington High School and was involved in theatre.